Matrix ions as internal standard for high mass accuracy matrix‐assisted laser desorption/ionization mass spectrometry imaging
نویسندگان
چکیده
منابع مشابه
High-accuracy molecular mass determination of proteins using matrix-assisted laser desorption mass spectrometry.
A method for obtaining protein molecular masses with an accuracy of approximately +/- 0.01% by matrix-assisted laser desorption using an internal calibrant is described. The technique allows accurate mass determinations of protein sample sizes as small as 1 pmol. High concentrations of organic and inorganic contaminants (e.g. 1 M urea) do not strongly affect either the signal intensity or the m...
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ژورنال
عنوان ژورنال: Rapid Communications in Mass Spectrometry
سال: 2021
ISSN: 0951-4198,1097-0231
DOI: 10.1002/rcm.9110